Evercyte

HME-1

The breast is prone to a number of benign as well as malignant changes and the search for factors that trigger such conditions is essential as is the development of novel therapeutic strategies targeting dysregulated mammary epithelial cells.

HME-1 – hTERT immortalized human mammary epithelial cell line with primary cell characteristics, amenable to gene editing using CRISPR/Cas9 for generation of isogenic tumor progression models.

Applications:

  • Study of breast cancer development
  • Use in phenotypic drug screening, orthogonal screening
  • Development of anti-tumor therapies
  • Performance of toxicological tests