Evercyte

Myoblasts

Progressive muscle weakness and atrophy as well as reduced regenerative capacity are essential characteristics of the aging process as well as certain muscular dystrophies. In order to study these processes and to develop novel therapeutic strategies human, highly differentiated in vitro models are essential.

LHCN-M2 – hTERT and cdk-4 immortalized myoblast progenitor cell line with superior differentiation capacity towards functional myotubes.

Application:

  • Study of myotoxicity and muscle damage
  • Screening for substances influencing muscle contraction
  • Establishment of disease models such as sarcopenia, muscle dystrophy
  • Drug screening and development