Evercyte

fHDF/TERT166, HDF/TERT1 and NHEK/SVTERT3-5

As an essential physiological barrier human skin plays important roles in e.g. the protection of the human body against pathogens, in heat regulation or evaporation control. Any perturbation of the skin becomes manifest in various diseases. In order to study processes such as inflammation, wound healing or tumor development human skin cells including fibroblasts and keratinocytes are important.

fHDF/TERT166 – hTERT immortalized human foreskin fibroblasts that are characterized by the ability to response to various cytokine stimuli similar to primary cells.
Cells from another donor are also available (HDF/TERT1).

Application

  • Study of extracellular matrix formation
  • Study of inflammation, wound healing, fibrosis and barrier function

NHEK/SVTERT3-5 – hTERT and SV40 early region immortalized human skin keratinocytes characterized by expression of typical marker proteins and the ability to differentiate towards functional 3D skin equivalents.
Cells from other donors are available upon request.

Application

  • Performing of toxicological tests
  • Study of processes such as wound healing
  • Investigation of barrier functions and drug transport